Vibrio Cholera 01 Antigen Test

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VCO 483
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Expected use

The One Step Vibrio Cholera O1 (VC O1) Test is a rapid and convenient in vitro immunochromatographic assay. It is used for the detection of vibrio cholera O1 Inaba and vibrio cholera O1 ogawa in stool samples or environmental water. Vibrio cholera O1 is widely recognized as one of the most important pathogens causing gastrointestinal disorders. This test provides a visual and qualitative result. Clinical experience and professional judgment should be sought to further evaluate the test results. It is intended for professional use.

Summary and explanation

V. cholera O1 is a gram-negative pathogen that causes epidemics of cholera, a devastating disease of immense global importance in many developing countries. It is generally transmitted to humans through contaminated food and water. Vibrio Cholera O1 is divided into 2 biotypes, E1 Tor and classical. Each of the biotypes contains 3 serotypes named Ogawa, Inaba, and Hikojima. The differentiation of the 3 forms of VC O1 has only limited epidemiological value.

Clinically, cholera can range from asymptomatic colonization to severe diarrhea with massive fluid loss, leading to dehydration, electrolyte disturbances, acidosis, circulatory disturbances, and death. V. cholera O1 causes this secretory diarrhea by colonizing the small intestine and producing a potent cholera toxin. Due to the clinical and epidemiological severity, it is essential to determine the presence of v. Cholerae in clinical samples, water and food so that public health authorities can carry out adequate monitoring and effective preventive measures. Nova One step V. Cholera O1 Test is a chromatographic immunoassay for the qualitative detection of V. cholera O1 (Vibrio cholera O1 Inaba and Vibrio cholera O1 ogawa) in human feces, rectal swab samples or water. The test is very sensitive to detect as little as 104 CFU / ml of V. cholera O1 in sample solution.