cDNA

Correlative Microscopy Insight on Electrodeposited Ultrathin Graphite Oxide Films

Here, we current a correlative microscopic evaluation of electrodeposited movies from catechol options in aqueous electrolytes. The movies had been ready in a miniaturized electrochemical cell and had been analyzed by equivalent location transmission electron microscopy, scanning transmission X-ray microscopy, and atomic power microscopy. Thanks to this mixed method, we’ve proven that the electrodeposited movies are constituted of ultrathin graphite […]

Hypothesis-driven quantitative fluorescence microscopy – the importance of reverse-thinking in experimental design

One of the challenges in trendy fluorescence microscopy is to reconcile the typical utilization of microscopes as exploratory devices with their rising and quickly increasing function as a quantitative instruments. The contribution of microscopy to observational biology will stay monumental owing to the enhancements in acquisition velocity, imaging depth, decision and biocompatibility of trendy imaging devices. However, the use of […]

Non-classical crystallisation pathway directly observed for a pharmaceutical crystal via liquid phase electron microscopy

Non-classical crystallisation (NCC) pathways are broadly accepted, nonetheless there’s conflicting proof relating to the intermediate phases of crystallisation, how they manifest and additional turn into crystals. Evidence from direct observations is particularly missing for small natural molecules, as distinguishing these low-electron dense entities from their comparable liquid-phase environment presents signal-to-noise ratio and distinction challenges. Here, Liquid Phase Electron Microscopy (LPEM) […]

Nonlinear Optical Microscopy: From Fundamentals to Applications in Live Bioimaging

A current problem in the sector of bioimaging is to picture very important, thick, and complicated tissues in actual time and in non-invasive mode. Among the totally different instruments obtainable for diagnostics, nonlinear optical (NLO) multi-photon microscopy permits label-free non-destructive investigation of physio-pathological processes in stay samples at sub-cellular spatial decision, enabling to examine the mechanisms underlying a number of […]

Cryptosporidium spp. and Giardia spp. (oo)cysts as target-organisms in sanitation and environmental monitoring: A review in microscopy-based viability assays

Cysts and (oo)cysts are the infective types of parasitic protozoa, as Giardia and Cryptosporidium, that are widespread and related to worldwide waterborne illnesses outbreaks. These microorganisms pose a problem to public well being, as they’re resistant to standard disinfection strategies, which make them essential parameters when evaluating inactivation effectivity. However, when (oo)cysts are targets, it’s difficult to deduce inactivation efficacy, […]