Antibodies that detect PI3K p85 alpha can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry and ELISA. These antibodies target PI3K p85 alpha in Human, Mouse, Rat, Porcine and Non-human primate samples. Our PI3K p85 alpha polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockout to confirm specificity to PI3K p85 alpha. Find the PI3K p85 alpha antibody that fits your needs. Choose from 1 of 28 PI3K p85 alpha antibodies, which have been validated in experiments with 28 publications and 124 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
Name:
Anti-PIK3R1 Antibody
Description:
Rabbit polyclonal antibody to PIK3R1
Specificity:
The antibody detects endogenous levels of total PIK3R1 protein.
Applications:
IHC
Reactivity:
Human
Immunogen:
Fusion protein corresponding to a region derived from internal residues of human phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
0.8mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Phosphatidylinositol 3-kinase (PIK3) is a signaling protein that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. Signaling is initiated when upstream tyrosine kinase receptors or G protein coupled receptors are bound by their ligands. It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. During insulin stimulation, it also binds to IRS-1. Mutations in the gene can result in Agammaglobulinemia 7, SHORT syndrome, or Immunodeficiency 36.
